Addendum to the Previous Post about Parkinson's Receptibility to Dopamine, and also Something of Psycheparous

Related post: Article: Asthma drugs may reduce Parkinson’s risk (yet another lap around the same track)


I've explained this before, and it deserves representation wherever talking about dopamine treatment for an ailment like Parkinson's, where the contemporary medical practitioner's presumption is that dopamine treatment of the ailment works at first, but eventually loses its effectiveness.



i.

With most all dopaminergics, when a person takes them, they're increasing both dopamine-availability, and adrenergic influence in their brain.

The more that dopamine is increased, the easier it is for a brain to connect information across synapses, to sync considering processes, and to process work to its conclusion and free up that pipeline space within a brain. However, as adrenergic influence is increased, the faster the brain tries to work, and the more dopamine is required to handle the increased workload of the brain. So, increasing adrenergic influence alongside dopamine is applying antithetical influences, and does a lot to undermine the goal of attending to states that are in need of an increase of dopamine, such as the dopamine deficiency ailment of Parkinson's.

When people taking dopaminergic drugs like meth get wired out, twitchy, and agitated, that's because of the adrenergic influence on the brain's processes over time outpacing the more temporary sought dopamine boost that those drugs give. The influence of the dopamine increase is immediate, and positive, but the influence on processes from the adrenergic increases is more inlaid, compiling over time, and lasting after the dopaminergic influence and benefit has worn off.

When taking dopaminergic Parkinson's medication, it initially helps because it is increasing dopamine, and that's always giving a positive work capacity boost to the brain, which immediately alleviates away as much of the top-layer negative impacts of the ailment as there is supplemented dopamine to address. But, at the same time, the brain is also being fed an increase in adrenergic influence, which will be feeding the source of the ailment all the while in the background.

So, over time, dopaminergics become less effective, not because dopamine stopped being what the brain needs, but because the adrenergic influence that was simultaneously being administered as a consequential component to the dopaminergic influence has contributed towards accelerating the ailment to the point that the dopamine aspect of the medication is no longer a significant influence against the ailment.

There aren't many dopaminergics that do much to inhibit adrenergic influence, but cocaine is one of them, and is what makes it such an effective treatment for mental stress ailments. I would say that if cocaine was used, rather than the various medicines that are currently used to treat Parkinson's, that there wouldn't be witnessed the same eventual ineffectiveness of the dopamine treatment as the ailment overcame its reach. And if used with understanding of Psycheparous to manage the movement of signals in a person's brain, then a full cure is in reach of anybody.

Keep in mind that what I've said would only apply to pure cocaine, as the things that street cocaine is cut with frequently add negative adrenergic influence of their own.



ii.

Conventional medicine is mired in an identity crisis, where it can't make up its mind whether it wishes to be good, or to be evil; whether it wants to cure people, or accomplish its ideology. When treating an ailment with part cure, part poison, then there isn't a full will present to cure that ailment, and the practitioner's interests are divided, and they end up failing to do good.



If asking a doctor: Do you want to cure this person, or not?

They might say: Yes, I want to cure that person.

And if it is then said to them: OK, so do what will cure that person.

Then their mind detaches itself from the context of the discussion, and they default into a programmed ideological determination of: We don't want to give people things that encourage non-medical substance use.

Which means that their honest answer to the question of 'Do you want to cure this person whose ailment is cause by lack of this specific thing, relative to the influence of these other things?' is: No, I do not want to cure that person - because the word 'cure' in that context is a stand-in which represents doing the very thing that is the person's cure. It's like a pointer, that references a container in which is held the considerations that fulfill the meaning of Cure for that particular person's situation.

Just as Jesus said 'you cannot serve mammon and God,' it is also true that a person cannot simultaneously serve ideology and still do what is good. An ideology is something that a person determines and sets up to replace the truth as their guide.



iii.

Just as considerations are polar, the signals that are considering through a person's brain present a workload for that brain. That workload carries a value to it, and dopamine-availability also presents a value of work potential. When there isn't enough dopamine to address presented workloads, it is possible for the workloads to do damage to that brain, as those signals are being pulled through the brain by Reason with force. Things can break, splintering one process into many that each need the same value of dopamine as the former one process did. Also, considering can collapse, and call fall into failure, including a failure that keeps considering over and over as a negative loop. And considerings that collapse into each other can form a black hole-like force, made by their compounding polarities all directing towards a point that draws in other consideration... and this is how granfalloons become created, as considerations are pulled out of the truthful context that gives them their meaning.

However, likewise, when a mind is filled positive truthful belief, the considering of that mind lifts it up with great strength into ever-greater truth, being the example of 'to whoever has, more will be given.' And many things will continually be resolved in that person, with them progressively filling up with light as they do so. Such considering represents the 'streams of living water' that Jesus spoke of, which he said become a 'spring of water welling up to eternal life.' As I've said, life is the movement created by considering, and considering is the movement created by considerations being considered by and flowing through other considerations.

Shrapnel

Article: Asthma drugs may reduce Parkinson’s risk (yet another lap around the same track)

Article: Asthma drugs may reduce Parkinson’s risk



i.

This isn't a mystery, and it shares the same explanation as a great multitude of other ailment-medication responses: Clenbuterol increases dopamine, and dopamine is the human brain's work fuel, and is what it uses to connect information across synapses. Any time dopamine is being increased, a brain's work capacity is being increased, and any time dopamine is reduced, a brain's capacity for work is reduced and stress is increased. Mental stress is merely a lack of dopamine availability within a brain relative to the amount of work a brain is trying to do, and is comparable to dehydration being a lack of water, and asphyxiation being a lack of oxygen.

Depression, anxiety, psychosis, ADHD, Parkinson's, Alzheimer's, schizophrenia... they all emerge from the state of stress that is dopamine deficiency, and they can all be effectively treated, even cured, by increasing dopamine while inhibiting adrenergic influence. The interrupted fetus development that is autism is again a case of insufficient dopamine availability within a pregnant mother, and autistic child-births can also be prevented by ensuring dopamine levels are high enough relative to other things in a pregnant mother.

Relatedly, what is called the placebo effect is positive belief reducing the micro states of uncertainty and worrying (those things causing considering in a brain, which is the work of a brain for which dopamine is required), which reduces the work in a brain, which frees up dopamine availability for a brain, which consequently leads to improved health.

Most dopaminergics have an unfavourable adrenergic influence alongside their positive dopaminergic influence, and increasing adrenergic influence worsens stress states. However, cocaine is one dopaminergic which does inhibit adrenergic response, and is excellent at inhibiting adrenergic response while greatly increasing dopamine availability within a brain.

In fact, when applied with understanding, it is possible to flush a severe and long-existing psychosis from a person in just a mere couple of hours, or less, using pure cocaine.



ii.

And don't forget Schizophrenia:

Exhibit A) Study Suggests Genetics Could Be The Root Cause Of Schizophrenia

"The findings may help explain the longstanding mystery of why brains from people with schizophrenia tend to have a thinner cerebral cortex with fewer synapses than unaffected individuals do," said a press statement from the Broad Institute of MIT and Harvard, whose experts took part in the study.

This is the brain's outer layer, often referred to as grey matter, involved in learning and memory."


Exhibit B) Mice Fed with Cocaine Show Growth in Brain Areas Linked with Learning, Memory

Looks like we have a match!


It's also the same reason why Methylene Blue helps against Alzheimer's, why coffee does the same and can help a person to live longer, why Modafinil is a "smart drug", why teenagers who lack what fuels a person's working memory capabilities end up using dopaminergic drugs while simplifying life helps prevent future mental illness, why poverty has the effect on people that it does, and why a million other dopaminergics help against a million dopamine-deficiency ailments:

An Eclectic Assortment of Articles, Which All Receive Resolution by Understanding Dopamine

A Few More for: An Eclectic Assortment of Articles...

The Third Entry Into "An Eclectic Assortment of Articles, Which All Receive Resolution by Understanding Dopamine"


It's all one thing - same cause, same solution.



iii.

Dopamine is only "reward" to a sociopath, who, because of their low consideration, associates the increased dopamine availability they experience from doing the types of things which they have determined to indicate that they are good little dogs as being a confirmation of their good little dogginess. This understanding is an inversion of the truth. What's actually happening is the same thing as happens with placebo:

"positive belief reducing the micro states of uncertainty and worrying (those things causing considering in a brain, which is the work of a brain for which dopamine is required), which reduces the work in a brain, which frees up dopamine availability for a brain, which consequently leads to improved health, cognitive strength, and positive feeling."


To someone that isn't a sociopath, dopamine is not "reward," or something that comes in the end, but physio-fuel, and what is required to be there in the beginning for proper and intended functionality, and for proficient and healthy development. To human physiology, it is the god-molecule.


Conventional medicine is firstly about ideology and profit, and not truth. The truth is that an enormous host of illnesses, particularly mental illnesses, all only emerge and branch from mental stress, which itself is simply a lack of dopamine availability in a brain relative to the amount of work that brain is trying to accomplish.

And much research that is done concerning related topics is primarily about the researcher seeking to experience peer-approved "reward" for conforming to and supporting a dogmatic ideology.


To sum the situation up from one angle: Institutional and academic medical doctrine is fake. It is the 21st century's equivalent of practising the four humours, and would only be more so if the four humours was a patented practice that earned its patent-holders money every time it was practised.



iv.

because it strips them of all the determinations they've used as justification for


Why do today's scientists revel in historical stories such as Galileo facing off against an institution of dogmatic ideologues who had all the evidence they were willing to consider to prove that Earth is the centre of the universe, when today's scientists are the same as the people Galileo faced off against?

And this is a pattern that has occurred throughout history: An individual person considers beyond conventions because of the greater belief they have within themselves, and by their consideration discovers new marvels that they then make known to everybody.

But all those who move by determinations oppose the greater consideration presented, because what is presented strips those people of all the determinations they've made to justify themselves, invalidating their prejudiced judgments, their perceptions of their statuses, their reputations as knowledgeable authorities...

In time, however, the greater truth become reinforced as indisputable, and then those whose truth is their determinations begin to make determinations about everything surrounding the new thing and begin turn it into an ideology, an institution, and a dogma. Then, sociopaths from all over flock to that thing and conform to it, not because they understand and know it, but because the appearance of consensus is what they take as truth. And they reinforce that thing with all kinds of extraneous infrastructures, and wave that thing all around as their "proof" of many other things, including why they're smarter than the dogmatic ideologues of history who did the same thing as they are doing - because now they have the right determination to conform to and invest their sentiments into.

But the truth is not a determination.



Related post: Addendum to the Previous Post about Parkinson's Receptibility to Dopamine, And Also Something of Psycheparous

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